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ACEROLA - Malpighia emarginata

Acerola has a potent antioxidant status.
Abstract Title:
Antioxidant activity, ascorbic acid and total phenol of exotic fruits occurring in Brazil.
Abstract Source:
Int J Food Sci Nutr. 2008 Sep 10:1-10. PMID: 18785051
Abstract Author(s):
Sandra Aparecida de Assis, Jose Carlos Rebuglio Vellosa, Iguatemy Lourenco Brunetti, Najeh Maissar Khalil, Katia Maria da Silva Cerqueira Leite, Antonio Baldo Geraldo Martins, Olga Maria Mascarenhas de Faria Oliveira
Excerpt: "The antioxidant activity, ascorbic acid and phenolic content were studied in 10 exotic fruits from Brazil: abiu, acerola, wax jambu, cashew, mamey sapote, carambola or star fruit, Surinam cherry, longan, sapodilla and jaboticaba. The ascorbic acid was determined by 2,6-dichloroindophenol titrimetic methods and total phenols were measured colorimetrically using the Folin-Ciocalteu reagent. The antioxidant activity was investigated with three different methods: hypochlorous acid scavenging activity, 2,2-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) radical cation decolorization assay, and 2,2-diphenyl-1-picrylhydrazyl radical scavenging method. The highest content of vitamin C (1,525.00 mg/100 g pulp) occurred in acerola. The total phenol content was higher in abiu, acerola, Surinam cherry and sapodilla. In relation to antioxidant activity, acerola has showed the great values in all three different methods tested. It was found that the fruits have a significant antioxidant effect when tested by each method, respectively, and these antioxidant capacities are promising. The sample concentration also influenced its antioxidant power."
Article Published Date : Sep 10, 2008
Study Type : In Vitro Study
Additional Links
Substances : Acerola : CK(11) : AC(8)
Diseases : Oxidative Stress : CK(3871) : AC(1382)
Acerola inhibits lung tumorigenesis in the mouse experimental model.

Abstract Title:
Effect of acerola cherry extract on cell proliferation and activation of ras signal pathway at the promotion stage of lung tumorigenesis in mice.
Abstract Source:
J Nutr Sci Vitaminol (Tokyo). 2002 Feb;48(1):69-72. PMID: 12026193
Abstract Author(s):
Isao Nagamine, Tsutomu Akiyama, Motoomi Kainuma, Hitomi Kumagai, Haruna Satoh, Kazuhiko Yamada, Tomohiro Yano, Hidetoshi Sakurai
Excerpt: "The present study was undertaken to estimate the effect of acerola cherry extract (ACE) pretreatment on cell proliferation and the activation of Ras signal pathway at a promotion stage of lung tumorigenesis in mice treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK). Pretreatment with ACE (dose, 70mg/kg body weight and 700 mg/kg body weight) inhibited increases in the levels of proliferating nuclear cell antigen and ornithine decarboxylase at the promotion stage. This treatment of ACE also suppressed the activation of Ras signal pathway at the same stage. These results suggest that ACE regulates abnormal cell growth at the promotion stage of lung tumorigenesis in mice treated with NNK as a result of suppression of the initiation stage."
Article Published Date : Feb 01, 2002
Study Type : Animal Study
Additional Links
Substances : Acerola : CK(11) : AC(8)
Diseases : Lung Cancer : CK(1043) : AC(393)


Influence of temperature, power density and processing time on the relative content of vitamins B in acerola juice. (a,b) Vitamin B2; (c,d) vitamin B3; (e,f) vitamin B5. The kinetics (a,c,e) was obtained applying a power density of 5000 W/L, and the response surface plots (b,d,f) were built using the data obtained at 15 min of ultrasound processing.



PubMed comprises more than 28 million citations for biomedical literature from MEDLINE, life science journals, and online books. 
In PubMed
There are  559 on Acerola.

10 Diseases Researched for Acerola:
Diabetes Insipidus12
Diabetes Mellitus: Type 212
Lung Cancer12
Advanced Glycation End products (AGE)11
Cancers: All11
Cancers: Multi-Drug Resistant11
Oxidative Stress11
Skin Diseases: Photo-Aging11

3 Pharmacological Actions Researched for Acerola:
Tyrosinase inhibitors11

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